Erscheinungsdatum: 03.02.2012, Medium: Buch, Einband: Gebunden, Titel: Advancements in Tumor Immunotherapy and Cancer Vaccines, Redaktion: Arnouk, Hilal, Verlag: IntechOpen, Sprache: Englisch, Rubrik: Medizin // Andere Fachgebiete, Seiten: 230, Informationen: HC gerader Rücken kaschiert, Gewicht: 710 gr, Verkäufer: averdo
Advancements in Tumor Immunotherapy and Cancer Vaccines ab 155 EURO
Progress in vitreo-retinal surgery is mercurial. Since this series is dedicated to new developments the reader is presented with a motley list of topics. The advancements described here may represent generally accepted progress in the field: New instruments, Macular hole surgery, Tumor biopsy. New ideas are set out to be tested for their benefit, for example: AMD surgery, Adjunctive pharmacotherapy. Reflections on incessant clinical problems in vitreo-retina surgery require superior scrutinization of established surgical techniques and indications: Posterior slippage, Inferior breaks, Subclinical retinal detachments. The editors will expand this list in future editions with topics like: new support for buckling surgery, enzyme assisted vitrectomy, new tamponades and other yet unknown fields of progress. TOC: Macular Holes. - Heavy Silicone Oil for Persistent Macular Holes. - The Role of Combined Adjunctive 5-Fluorouracil and Low Molecular Weight Heparin in Proliferative. - Vitreoretinopathy Prevention. - Slippage of the Retina: What CausesIt and How Can It Be Prevented?. - Complete and Early Vitrectomy for Endophthalmitis (CEVE) as Today's Alternative to the Endophthalmitis Vitrectomy Study. - Treatment of Acute Bacterial Endophthalmitis After Cataract Surgery Without Vitrectomy. - New Instruments in Vitrectomy. - 25-Gauge Biopsy of Uveal Tumors. - Vitrectomy Against Floaters. - Treatment of Retinal Detachment from Inferior Breaks with Pars Plana Vitrectomy. - Subclinical Retinal Detachment. - Autologous Translocation of the Choroid and RPE in Patients with Geographic Atrophy
One of the greatest challenges facing the computational engineering community is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, the biomedical sciences and medicine. The Computational Biomechanics for Medicine series provides an opportunity for specialists in computational biomechanics to present their latest methodologies and advancements. This 5th edition comprises nine of the latest developments in both fundamental science and patient-specific applications, from researchers in Australia, New Zealand, USA, UK, France, Ireland and China. Some of the interesting topics discussed are: cellular mechanics; tumor growth and modeling; medical image analysis and both patient-specific fluid dynamics and solid mechanic simulations.
miRNAs are a class of endogenous, small non-protein coding RNA molecules (~ 22 nucleotides) which are novel post-transcriptional regulators of gene expression. Since we have hundreds of miRNAs, the major challenge is now to understand their specific biological function. In fact the experimental evidence suggests that signaling pathways could be ideal candidates for miRNA-mediated regulation. Several studies suggest that miRNAs affect the responsiveness of cells to signaling molecules such as WNT, Notch, TGF-ss and EGFR. Altered expression of particular miRNAs has been implicated in the onset and development of cancer and could be used as potential biomarkers for the disease. Recently, many studies have found miRNAs have crucial regulatory roles in Cancer stem cells (CSCs) a kind of tumor initiating cells (TICs) and dormancy. Findings also suggest that DNA methylation may be important in regulating the expression of many miRNAs in several cancer initiating cells. Several miRNAs are known to either upregulated or downregulated in CSCs when compared to non-cancerous cells from the same tissues. CSCs are a small subpopulation of cells identified in a variety of tumors and involve in self-renewal, differentiation, chemoresistance and tumorigenesis. The volume will give a comprehensive account of important advancements in the area of miRNAs and cancer.
Current applications and recent advances in genomics andproteomics Genomics and Proteomics Engineering in Medicine andBiology presents a well-rounded, interdisciplinary discussionof a topic that is at the cutting edge of both molecular biologyand bioengineering. Compiling contributions by established experts,this book highlights up-to-date applications of biomedicalinformatics, as well as advancements in genomics-proteomics areas.Structures and algorithms are used to analyze genomic data anddevelop computational solutions for pathological understanding. Topics discussed include: * Qualitative knowledge models * Interpreting micro-array data * Gene regulation bioinformatics * Methods to analyze micro-array * Cancer behavior and radiation therapy * Error-control codes and the genome * Complex life science multi-database queries * Computational protein analysis * Tumor and tumor suppressor proteins interactions
Because of tremendous advancements in research, neurosurgical oncology has become increasingly complex, and it is imperative that physicians have scientific evidence to guide and defend their decision making as they strive to provide the best patient care. Controversies in Neuro-Oncology: Best Evidence Medicine for Brain Tumor Surgery, written by world-renowned experts, is a comprehensive guide that compiles, synthesizes, and summarizes the most relevant scientific literature available in neurosurgical oncology. It provides objective recommendations based on the data found in the literature, giving physicians the information they need to make fully informed treatment decisions. Key Features: - An opening chapter, Introduction to Best Evidence Medicine, illustrates how the authors rate the viability of the data presented - Authors discuss in detail commonly disputed topics specific to tumor type, such as the roles of surgery and gross total resection as well as radiosurgery options - Expert recommendation boxes highlight #takeaways# for the reader - Summary tables distill abundant scientific evidence and emphasize the main conclusions of published studies
Current applications and recent advances in genomics and proteomics Genomics and Proteomics Engineering in Medicine and Biology presents a well-rounded, interdisciplinary discussion of a topic that is at the cutting edge of both molecular biology and bioengineering. Compiling contributions by established experts, this book highlights up-to-date applications of biomedical informatics, as well as advancements in genomics-proteomics areas. Structures and algorithms are used to analyze genomic data and develop computational solutions for pathological understanding. Topics discussed include: * Qualitative knowledge models * Interpreting micro-array data * Gene regulation bioinformatics * Methods to analyze micro-array * Cancer behavior and radiation therapy * Error-control codes and the genome * Complex life science multi-database queries * Computational protein analysis * Tumor and tumor suppressor proteins interactions
Neuroblastoma (NBL) is the most common extracranial solid tumor of childhood, with about 700 new cases of neuroblastoma seen each year in the United States. The 5-year survival rate for children with high-risk NBL is only 50-60%, and this survival rate has not improved over the last 10 years. High-risk patients receive multimodality treatment, including chemotherapy, surgery, radiation therapy, biologic therapy and immunotherapy, all of which are associated with significant morbidity. Recent years have seen many advances in treatment of neuroblastoma, including therapeutic MIBG, immunotherapy, and personalized targeted therapy based on the genetic alterations seen in the tumor. The primary objective of this book is to provide the readers with a comprehensive review of neuroblastoma, from clinical aspects and the currently available treatment to recent advancements and future directions in the field of NBL treatment. The topics and chapters have been compiled keeping in mind a diverse group of readers in different areas of specialty such as pediatric oncology, surgery, radiation oncology, and immunology, as well as physician scientists and basic researchers working in the field of neuroblastoma.