Angebote zu "Assays" (42 Treffer)

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Tumor Angiogenesis Assays
89,89 € *
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Erscheinungsdatum: 27.06.2018, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: Tumor Angiogenesis Assays, Titelzusatz: Methods and Protocols, Auflage: Softcover reprint of the original 1st ed. 2016, Redaktion: Ribatti, Domenico, Verlag: Springer New York // Springer US, Sprache: Englisch, Rubrik: Allgemeinmedizin // Diagnostik, Therapie, Seiten: 208, Informationen: Paperback, Gewicht: 402 gr, Verkäufer: averdo

Anbieter: averdo
Stand: 18.09.2020
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Tumor Angiogenesis Assays
101,49 € *
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Tumor Angiogenesis Assays ab 101.49 € als Taschenbuch: Methods and Protocols. Softcover reprint of the original 1st ed. 2016. Aus dem Bereich: Bücher, Wissenschaft, Medizin,

Anbieter: hugendubel
Stand: 18.09.2020
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Prevention and Early Detection of Human Tumor
33,16 € *
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In 2014 World Health Organization (WHO) reported that during the next 25 years the number of cancer cases would increase by about 70% world-wide. In order to deal with this dramatically increase, WHO suggested to focus on prevention and early detection of human tumor by health screening. We have worked on this topic for more than 30 years resulting in assays for prevention and early detection of human cancer useful in health screening of cancer, for prognoses of relapse and survival of cancer patients and monitoring the effect of cancer treatment. The prevention assay is based on markers related to oxidative stress (8-oxo-dG) and the early detection of human tumors on biomarkers associated with tumor proliferation rate (thymidine kinase 1, TK1). In combination with functional foods it is possible to reduce the risk of develop mutations leading to cancer. People with elevated TK1 levels in their blood show a 3-5 times higher risk to develop malignancy within 6 years. Prevention strategy would reduce the number of cancer patients, and early detection and early treatment would increase the possibility, not only to prolong patient's life, but also to cure them.

Anbieter: buecher
Stand: 18.09.2020
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Prevention and Early Detection of Human Tumor
33,16 € *
ggf. zzgl. Versand

In 2014 World Health Organization (WHO) reported that during the next 25 years the number of cancer cases would increase by about 70% world-wide. In order to deal with this dramatically increase, WHO suggested to focus on prevention and early detection of human tumor by health screening. We have worked on this topic for more than 30 years resulting in assays for prevention and early detection of human cancer useful in health screening of cancer, for prognoses of relapse and survival of cancer patients and monitoring the effect of cancer treatment. The prevention assay is based on markers related to oxidative stress (8-oxo-dG) and the early detection of human tumors on biomarkers associated with tumor proliferation rate (thymidine kinase 1, TK1). In combination with functional foods it is possible to reduce the risk of develop mutations leading to cancer. People with elevated TK1 levels in their blood show a 3-5 times higher risk to develop malignancy within 6 years. Prevention strategy would reduce the number of cancer patients, and early detection and early treatment would increase the possibility, not only to prolong patient's life, but also to cure them.

Anbieter: buecher
Stand: 18.09.2020
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Predictive Biomarkers in Oncology
124,50 € *
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"Precision/personalized or stratified medicine" refers to the tailoring of medical treatment or drug administration to the individual characteristics of each patient treatment. It does not literally mean that a pharmaceutical company makes a drug for an individual patient for consumption and treatment but rather means the ability to stratify (or classify) individuals into sub-populations that differ in their responsiveness to a specific drug. A marker that provides information on the likely response to therapy, i.e., either in terms of tumor shrinkage or survival of the patient is termed "predictive biomarker". Despite their promise in precision medicine and the explosion of knowledge in this area, there is not a single source on this subject that puts all this evidence together in a concise or richly illustrated and easy to understand manner. This book provides a collection of ingeniously organized, well-illustrated and up-to-date authoritative chapters divided into five sections that are clear and easy to understand. Section one provides an overview of biomarkers, introduces the basic terminologies, definitions, technologies, tools and concepts associated with this subject in the form of illustrations/graphics, photographs and concise texts. Several recent biomarker endeavors that have been initiated and funded by the National Cancer Institute, National Institutes of Health, FDA and other International organizations are presented. Section two involves the signaling pathways controlling cell growth and differentiation altered in cancer. This section analyzes how predictive biomarkers are altered (expressed or amplified) across cancer types. Section three explores how predictive biomarkers play a role in patient stratification and tailored treatment in relationship to specific cancers. In addition, it includes discussion on the various precision medicine initiatives that are going on across the globe (e.g. TARGET, NCI-MATCH, BATTLE, SHIVA, etc.). Section four discusses: (a) how pharmaceutical companies validate predictive biomarker assays and accompanying companion diagnostics either internally or externally with partner companies such as central laboratories or clinical research organizations, and (b) how predictive biomarker tests fall under the oversight of US FDA, Centers for Medicare & Medicaid Services (CMS) and state laws. Section five wraps up novel agents and targets that are being used as targets for cancer therapeutics. The biomarkers associated with these protocols will also be presented. Throughout the book, sidebars, special interest boxes and illustrations are used to explain terms that are either newly introduced, uncommon, or specialized. Predictive Biomarkers in Oncology will serve as a definitive guide for practicing pathologists, oncologists, basic researchers, and personnel in the pharmaceutical or diagnostic industry interested in learning how "predictive biomarkers" are used in precision cancer therapy.

Anbieter: buecher
Stand: 18.09.2020
Zum Angebot
Predictive Biomarkers in Oncology
124,50 € *
ggf. zzgl. Versand

"Precision/personalized or stratified medicine" refers to the tailoring of medical treatment or drug administration to the individual characteristics of each patient treatment. It does not literally mean that a pharmaceutical company makes a drug for an individual patient for consumption and treatment but rather means the ability to stratify (or classify) individuals into sub-populations that differ in their responsiveness to a specific drug. A marker that provides information on the likely response to therapy, i.e., either in terms of tumor shrinkage or survival of the patient is termed "predictive biomarker". Despite their promise in precision medicine and the explosion of knowledge in this area, there is not a single source on this subject that puts all this evidence together in a concise or richly illustrated and easy to understand manner. This book provides a collection of ingeniously organized, well-illustrated and up-to-date authoritative chapters divided into five sections that are clear and easy to understand. Section one provides an overview of biomarkers, introduces the basic terminologies, definitions, technologies, tools and concepts associated with this subject in the form of illustrations/graphics, photographs and concise texts. Several recent biomarker endeavors that have been initiated and funded by the National Cancer Institute, National Institutes of Health, FDA and other International organizations are presented. Section two involves the signaling pathways controlling cell growth and differentiation altered in cancer. This section analyzes how predictive biomarkers are altered (expressed or amplified) across cancer types. Section three explores how predictive biomarkers play a role in patient stratification and tailored treatment in relationship to specific cancers. In addition, it includes discussion on the various precision medicine initiatives that are going on across the globe (e.g. TARGET, NCI-MATCH, BATTLE, SHIVA, etc.). Section four discusses: (a) how pharmaceutical companies validate predictive biomarker assays and accompanying companion diagnostics either internally or externally with partner companies such as central laboratories or clinical research organizations, and (b) how predictive biomarker tests fall under the oversight of US FDA, Centers for Medicare & Medicaid Services (CMS) and state laws. Section five wraps up novel agents and targets that are being used as targets for cancer therapeutics. The biomarkers associated with these protocols will also be presented. Throughout the book, sidebars, special interest boxes and illustrations are used to explain terms that are either newly introduced, uncommon, or specialized. Predictive Biomarkers in Oncology will serve as a definitive guide for practicing pathologists, oncologists, basic researchers, and personnel in the pharmaceutical or diagnostic industry interested in learning how "predictive biomarkers" are used in precision cancer therapy.

Anbieter: buecher
Stand: 18.09.2020
Zum Angebot
Tumor Angiogenesis Assays
101,49 € *
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Tumor Angiogenesis Assays ab 101.49 EURO Methods and Protocols. Softcover reprint of the original 1st ed. 2016

Anbieter: ebook.de
Stand: 18.09.2020
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Synthesis & biological investigation of fluorin...
49,00 € *
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Integrins are cell surface receptors that take part in cell cell adhesion and cell extracellular matrix (ECM) adhesion events as well as in cell migration and cell signaling. 5 1 integrins are expressed on a wide range among brain tumor cells. In this study, an intermediate spiroisoxazolinopyrrole of the most specific 5 1 integrin antagonist SJ749 was synthesized. Fischer esterification reaction, Swern oxidation, and Wittig olefination were performed. Next, fluorinated diaminopropionate molecules were synthesized for coupling to SJ749 instead of the (2,4,6-trimethylphenyl) diaminopropionate. Finally, the biological evaluation of the molecules synthesized was performed. These assays included cytotoxicity and cell proliferation.

Anbieter: Dodax
Stand: 18.09.2020
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Laboratory Techniques with Applicability in Med...
41,90 € *
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The book is recommended to young researchers in experimental medicine. The topics cover a wide range of state of the art methods: microbiological techniques including whole genome sequencing, new biomarkers in sepsis monitoring, multiparametric luminescent cellular viability assays and antioxidant activity measurements, basic considerations of circulating tumor cells and the problematics of melanocytic nevi in children.

Anbieter: Dodax
Stand: 18.09.2020
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