Angebote zu "Radioimmunotherapy" (6 Treffer)

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Radioimmunotherapy
39,00 € *
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Radioimmunotherapy (RIT) uses an antibody labeled with a radionuclide to deliver cytotoxic radiation to a target cell. In cancer therapy, an antibody with specificity for a tumor-associated antigen is used to deliver a lethal dose of radiation to the tumor cells. The ability for the antibody to specifically bind to a tumor-associated antigen increases the dose delivered to the tumor cells while decreasing the dose to normal tissues. By its nature, RIT requires a tumor cell to express an antigen that is unique to the neoplasm or is not accessible in normal cells.

Anbieter: Dodax
Stand: 06.12.2020
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Astatine-211 Radioimmunotherapy of Ovarian Cancer
112,00 CHF *
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Alpha-particle emitting radionuclides have recently obtained an increased attention when considering new strategies for treating disseminated cancer. Astatine-211(At211), that emits alpha particles is one among the most promising nuclides in this respect. In the PhD thesis by Jörgen Elgqvist (registered Medical Physicist) presented in this book At211 was used for evaluating the therapeutic efficacy, myelotoxicity, and radiation dosimetry in the treatment of intraperitoneally disseminated micrometastatic ovarian cancer in mice. In order to specifically irradiate the tumor cells At211 was labeled to monoclonal antibodies, targeting certain cell surface epitopes. The PhD thesis, presented on pages 1-148, received the Assar Gabrielsson Award in 2009 as 'The best PhD thesis in cancer research from the University of Gothenburg during the past three years'. In addition to the PhD thesis two animal studies are also presented in an appendix. The first study investigated the therapeutic efficacy with intraperitoneal alpha-radioimmunotherapy using different specific radioactivities. The second study invesigated the therapeutic efficacy using repeated alpha-radioimmunotherapy.

Anbieter: Orell Fuessli CH
Stand: 06.12.2020
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Molecular Imaging
275,90 CHF *
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The continuous progress in the understanding of molecular processes of disease formation and progression attributes an increasing importance to biomedical molecular imaging methods. The purpose of this workshop was to discuss and overview multiple applications and emerging technologies in the area of diagnostic imaging including its fundamental capabilities in preclinical research, the opportunities for medical care, and the options involving therapeutic concepts. The book provides the reader with state-of-the-art information on the different aspects of diagnostic imaging, illuminating new developments in molecular biology, imaging agents and molecular probe design, and therapeutic techniques. TOC:B. Tavitian: Oligonucleotides as Radiopharmaceutical.- D. Piwnica-Worms, K. Luker: Imaging Protein-Protein Interactions in Whole Cells and Living Animals.- G. Paganelli: Pre-Targeted Radioimmunotherapy.- T.F. Hany, G.K. von Schulthess: PET/CT: Combining Function and Morphology.- S. Aimé et al: High Relaxivity Contrast Agents for MRI and Molecular Imaging.- D. Parker, Y. Bretonnière: Luminescent Lathanide Complexes as Sensors and Imaging Probes.- Ch. Bremer: Imaging of Proteases for Tumor Detection and Differentiation.- Klibanov: Targeted Ultrasound Imaging.- Lowik et al: Non-Invasive Real-time in vivo Bioluminescent Imaging (BLI) of Gene Expression and of Tumor Progression and Metastasis.- N. Solban et al: Targeted Optical Imaging and Photodynamic Therapy.- H. Maecke: Radiolabeled Peptides in Nuclear Oncology; Influence of Peptide Structure and Labeling Strategy on Pharmacology.

Anbieter: Orell Fuessli CH
Stand: 06.12.2020
Zum Angebot
Astatine-211 Radioimmunotherapy of Ovarian Cancer
59,99 € *
ggf. zzgl. Versand

Alpha-particle emitting radionuclides have recently obtained an increased attention when considering new strategies for treating disseminated cancer. Astatine-211(At211), that emits alpha particles is one among the most promising nuclides in this respect. In the PhD thesis by Jörgen Elgqvist (registered Medical Physicist) presented in this book At211 was used for evaluating the therapeutic efficacy, myelotoxicity, and radiation dosimetry in the treatment of intraperitoneally disseminated micrometastatic ovarian cancer in mice. In order to specifically irradiate the tumor cells At211 was labeled to monoclonal antibodies, targeting certain cell surface epitopes. The PhD thesis, presented on pages 1-148, received the Assar Gabrielsson Award in 2009 as 'The best PhD thesis in cancer research from the University of Gothenburg during the past three years'. In addition to the PhD thesis two animal studies are also presented in an appendix. The first study investigated the therapeutic efficacy with intraperitoneal alpha-radioimmunotherapy using different specific radioactivities. The second study invesigated the therapeutic efficacy using repeated alpha-radioimmunotherapy.

Anbieter: Thalia AT
Stand: 06.12.2020
Zum Angebot
Molecular Imaging
229,90 € *
ggf. zzgl. Versand

The continuous progress in the understanding of molecular processes of disease formation and progression attributes an increasing importance to biomedical molecular imaging methods. The purpose of this workshop was to discuss and overview multiple applications and emerging technologies in the area of diagnostic imaging including its fundamental capabilities in preclinical research, the opportunities for medical care, and the options involving therapeutic concepts. The book provides the reader with state-of-the-art information on the different aspects of diagnostic imaging, illuminating new developments in molecular biology, imaging agents and molecular probe design, and therapeutic techniques. TOC:B. Tavitian: Oligonucleotides as Radiopharmaceutical.- D. Piwnica-Worms, K. Luker: Imaging Protein-Protein Interactions in Whole Cells and Living Animals.- G. Paganelli: Pre-Targeted Radioimmunotherapy.- T.F. Hany, G.K. von Schulthess: PET/CT: Combining Function and Morphology.- S. Aimé et al: High Relaxivity Contrast Agents for MRI and Molecular Imaging.- D. Parker, Y. Bretonnière: Luminescent Lathanide Complexes as Sensors and Imaging Probes.- Ch. Bremer: Imaging of Proteases for Tumor Detection and Differentiation.- Klibanov: Targeted Ultrasound Imaging.- Lowik et al: Non-Invasive Real-time in vivo Bioluminescent Imaging (BLI) of Gene Expression and of Tumor Progression and Metastasis.- N. Solban et al: Targeted Optical Imaging and Photodynamic Therapy.- H. Maecke: Radiolabeled Peptides in Nuclear Oncology; Influence of Peptide Structure and Labeling Strategy on Pharmacology.

Anbieter: Thalia AT
Stand: 06.12.2020
Zum Angebot

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