Erscheinungsdatum: 19.10.2010, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: Targeted Radionuclide Tumor Therapy, Titelzusatz: Biological Aspects, Auflage: Softcover reprint of hardcover 1st ed. 2008, Redaktion: Adams, Gregory P. // Carlsson, Jorgen // Stigbrand, Torgny, Verlag: Springer Netherlands // Springer Netherland, Sprache: Englisch, Schlagworte: Nuklearmedizin // Medizinische Bildverarbeitung: Radiologie, Rubrik: Allgemeinmedizin // Diagnostik, Therapie, Seiten: 416, Informationen: Paperback, Gewicht: 628 gr, Verkäufer: averdo
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Radioimmunotherapy (RIT) uses an antibody labeled with a radionuclide to deliver cytotoxic radiation to a target cell. In cancer therapy, an antibody with specificity for a tumor-associated antigen is used to deliver a lethal dose of radiation to the tumor cells. The ability for the antibody to specifically bind to a tumor-associated antigen increases the dose delivered to the tumor cells while decreasing the dose to normal tissues. By its nature, RIT requires a tumor cell to express an antigen that is unique to the neoplasm or is not accessible in normal cells.
This pocket book offers a succinct but comprehensive overview of the role of PET/CT in radiotherapy planning. Individual chapters are devoted to specific application of the technique to particular tumor types, including non-small cell lung, gastrointestinal, head and neck squamous cell, prostate, gynecological, and pediatric tumors. Helpful information is also presented on the practical implementation of PET/CT in routine oncological practice. Technical and logistical issues are discussed, and guidance provided on potential problems and pitfalls and available solutions. The book will be invaluable in assisting readers to exploit PET/CT's ability to significantly improve delineation of tumor tissue through the addition of metabolic information to structural imaging data, thereby avoiding unnecessary radiation injury and associated complications while enhancing therapeutic effects and minimizing the risk of marginal recurrences. It is published within the Springer series Clinicians' Guides to Radionuclide Hybrid Imaging , compiled under the auspices of the British Nuclear Medicine Society.